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Article

Association of ABCC2 polymorphism and gender with high-density lipoprotein cholesterol response to simvastatin.

Pharmacogenomics - 1 Sept 2018

Liu Na, Yang Guihua, Hu Mei, Cai Yuyu, Hu Zhiying, Jia Chundi, Zhang Man

Abstract excerpt

AIM: The clinical benefits of lipid-lowering therapy with statins are widely recognized. However, the lipid-lowering efficacy of statins shows significant differences between individuals. ABCC2 has been demonstrated to contribute to the transmembrane transport of the substrate compounds. The ABCC2 SNPs may be important factors that affect individual differences in clinical drug response. The aim of this study was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30024814
DOI: 10.2217/pgs-2018-0084

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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