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Article

Genome-wide association study of therapeutic response to statin drugs in cardiovascular disease.

Scientific reports - 3 Aug 2024

Dabiri Hamed, Mortezaei Zahra

Abstract excerpt

Cardiovascular disease (CVD) is one of the main causes of death in the world. The increased level of blood cholesterol is significantly correlated to CVD incidents. Statins are a group of drugs that decrease the synthesis of cholesterol in the liver by inhibiting the final enzyme of the pathway named HMG-CoA reductase. Several investigations showed that different patients give different responses to the...

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Identifiers

PMID: 39097628
DOI: 10.1038/s41598-024-68665-4
PMCID: PMC11297937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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