Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life.

Scientific reports - 18 Jul 2018

Song Yong, Aguilar Ruth, Guo Jing, Manaca Maria Nelia, Nhabomba Augusto, Berthoud Tamara Katherine, Khoo Siew-Kim, Wiertsema Selma, Barbosa Arnoldo, Quintó Llorenç, Laing Ingrid A, Mayor Alfredo, Guinovart Caterina, Alonso Pedro L, LeSouëf Peter N, Dobaño Carlota, Zhang Guicheng Brad

Abstract excerpt

Using a well-designed longitudinal cohort, we aimed to identify cytokines that were protective against malaria and to explore how they were influenced by genetic and immunological factors. 349 Mozambican pregnant women and their newborn babies were recruited and followed up for malaria outcomes until 24 months of age. Six Th1 cytokines in cord blood were screened for correlation with malaria incidence, of which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Fetal Blood

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-12

Share to Leukocytes, Mononuclear

Share to Malaria, Falciparum

Share to Plasmodium falciparum

Share to Pregnancy

Share to Pregnancy Complications, Parasitic

Source

Open in PubMed Open full text

Identifiers

PMID: 30022038
DOI: 10.1038/s41598-018-29179-y
PMCID: PMC6052074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life.PMID 30022038Read ↗

A functional promoter variant in IL12B predisposes to cerebral malaria.Semantic proximity Read ↗

Interleukin-10 (IL-10) polymorphisms are associated with IL-10 production and clinical malaria in young children.Semantic proximity Read ↗

A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide productionSemantic proximity Read ↗

Association of variants in IL1B, TLR9, TREM1, IL10RA, and CD3G and Native American ancestry on malaria susceptibility in Colombian populations.Semantic proximity Read ↗

Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria.Semantic proximity Read ↗

IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil.Semantic proximity Read ↗

Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children.Semantic proximity Read ↗

Hemoglobin Genotypes Modulate Inflammatory Response to Plasmodium Infection.Semantic proximity Read ↗

Signatures of divergent antimalarial treatment responses in peripheral blood from infants and adults in MalawiSemantic proximity Read ↗

Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production.Semantic proximity Read ↗

Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children.Semantic proximity Read ↗

Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.