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Article

Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production.

Human genetics - 1 Dec 2008

Ouma Collins, Davenport Gregory C, Were Tom, Otieno Michael F, Hittner James B, Vulule John M, Martinson Jeremy, Ong'echa John M, Ferrell Robert E, Perkins Douglas J

Abstract excerpt

Plasmodium falciparum malaria is one of the leading global causes of morbidity and mortality with African children bearing the highest disease burden. Among the various severe disease sequelae common to falciparum malaria, severe malarial anemia (SMA) in pediatric populations accounts for the gre...

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Identifiers

PMID: 18972133
DOI: 10.1007/s00439-008-0578-5
PMCID: PMC2723852

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18972133-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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