Article
Single-cell observations reveal intermediate transcriptional silencing states.
Molecular cell - 21 Jul 2006
Xu Eugenia Y, Zawadzki Karl A, Broach James R
Abstract excerpt
Analysis of transcriptional silencing in Saccharomyces has provided valuable insights into heterochromatin formation and function. However, most of these studies revealed only the average behaviors of populations of cells. Here, we examined transcriptional silencing by monitoring individual yeast cells carrying distinguishable fluorescent reporter genes inserted at two different silent loci. These studies showed...
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