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Article

Single-cell observations reveal intermediate transcriptional silencing states.

Molecular cell - 21 Jul 2006

Xu Eugenia Y, Zawadzki Karl A, Broach James R

Abstract excerpt

Analysis of transcriptional silencing in Saccharomyces has provided valuable insights into heterochromatin formation and function. However, most of these studies revealed only the average behaviors of populations of cells. Here, we examined transcriptional silencing by monitoring individual yeast cells carrying distinguishable fluorescent reporter genes inserted at two different silent loci. These studies showed...

Topics

Acetyltransferases
Fluorescent Dyes
Gene Expression Regulation, Fungal
Gene Silencing
Genes, Reporter
Histone Acetyltransferases
Histones
Phenotype
Promoter Regions, Genetic
Saccharomyces
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Silent Information Regulator Proteins, Saccharomyces cerevisiae

Transcription, Genetic

Transcriptional Activation

Source

Identifiers

PMID: 16857588
DOI: 10.1016/j.molcel.2006.05.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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