Article
Noisy silencing of chromatin.
Developmental cell - 1 Aug 2006
Rando Oliver J, Paulsson Johan
Abstract excerpt
Chromatin-based repression is a major mechanism for epigenetically heritable variation. Work in the July 21 issue of Molecular Cell quantitatively examines transcriptional silencing in individual yeast cells, demonstrating locus-specific effects and finding that different silencing mutants exhibit qualitatively distinct single-cell defects.
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