The genetics of Graves' disease.

doi:10.1016/s0889-8529(05)70130-4

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Article

The genetics of Graves' disease.

Endocrinology and metabolism clinics of North America - 1 Jun 2000

Gough S C

Abstract excerpt

Graves' disease is a complex autoimmune disorder in which several genetic susceptibility loci and environmental factors are likely to contribute to the development of disease. HLA and the CTLA-4 gene region have been established as susceptibility loci, although the magnitude of their contributions seems to vary between data sets and geographic populations. Genome-wide searches are beginning to identify new loci,...

Topics

Abatacept
Antigens, CD
Antigens, Differentiation
CTLA-4 Antigen
Genetic Linkage
Genetic Predisposition to Disease
Graves Disease
HLA Antigens
Humans
Immunoconjugates
Major Histocompatibility Complex
T-Lymphocytes, Cytotoxic

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Open in PubMed

Identifiers

PMID: 10874528
DOI: 10.1016/s0889-8529(05)70130-4

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