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Article

Analysis of HLA Variants and Graves' Disease and Its Comorbidities Using a High Resolution Imputation System to Examine Electronic Medical Health Records.

Frontiers in endocrinology - 1 Jan 2022

Liao Wen-Ling, Liu Ting-Yuan, Cheng Chi-Fung, Chou Yu-Pao, Wang Tzu-Yuan, Chang Ya-Wen, Chen Shih-Yin, Tsai Fuu-Jen

Abstract excerpt

Hyperthyroidism is a prevalent endocrine disorder, and genetics play a major role in the development of thyroid-associated diseases. In particular, the inheritance of HLA has been demonstrated to induce the highest susceptibility to Graves' disease (GD). However, thus far, no studies have reported the contribution of HLA to the development of GD and the complications that follow. Thus, in the present study, to...

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Identifiers

PMID: 35321340
DOI: 10.3389/fendo.2022.842673
PMCID: PMC8936090

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