Article
The HLA-DRB1 gene and Graves disease in Taiwanese children: a case-control and family-based study.
Tissue antigens - 1 Sept 2012
Wu Y-L, Chang T-Y, Chu C-C, Huang C-Y, Lo F-S, Ting W-H, Lin C-H, Lin M, Chiu P-C, Lin C-L, Chen W-F, Lee Y-J
Abstract excerpt
Graves disease (GD) is an autoimmune thyroid disease with a female preponderance and a wide range of ages at onset, and human leukocyte antigen (HLA) gene plays a primary role in the susceptibility to GD. We aim to investigate the associations between HLA-DRB1 alleles and Taiwanese children with GD by both case-control and family-based studies. A total of 241 unrelated children with GD, 539 healthy controls, 115...
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