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Article

A refined study of FCRL genes from a genome-wide association study for Graves' disease.

PloS one - 1 Jan 2013

Zhao Shuang-Xia, Liu Wei, Zhan Ming, Song Zhi-Yi, Yang Shao-Ying, Xue Li-Qiong, Pan Chun-Ming, Gu Zhao-Hui, Liu Bing-Li, Wang Hai-Ning, Liang Liming, Liang Jun, Zhang Xiao-Mei, Yuan Guo-Yue, Li Chang-Gui, Chen Ming-Dao, Chen Jia-Lun, Gao Guan-Qi, Song Huai-Dong

Abstract excerpt

To pinpoint the exact location of the etiological variant/s present at 1q21.1 harboring FCRL1-5 and CD5L genes, we carried out a refined association study in the entire FCRL region in 1,536 patients with Graves' disease (GD) and 1,516 sex-matched controls by imputation analysis, logistic regression, and cis-eQTL analysis. Among 516 SNPs with P<0.05 in the initial GWAS scan, the strongest signals associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23505439
DOI: 10.1371/journal.pone.0057758
PMCID: PMC3591391

Genes

FCRL3
FCRL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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