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A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease.

Clinical endocrinology - 1 Dec 2018

Liu Wei, Zhang Qian-Yue, Yuan Fei-Fei, Wang Hai-Ning, Zhang Le-Le, Ma Yu-Ru, Ye Xiao-Ping, Zhang Man-Man, Song Zhi-Yi, Li Sheng-Xian, Du Wen-Hua, Liang Jun, Zhang Xiao-Mei, Gao Guan-Qi, Zhao Shuang-Xia, Chen Feng-Ling, Song Huai-Dong

Abstract excerpt

OBJECTIVE: We aimed to investigate the six susceptibility loci of GD identified from European population in Chinese Han population and further to estimate the genetic heterogeneity of them in stratification of our GD patients. DESIGN: Dense mapping studies based on GWAS. PATIENTS: A total of 1536 GD patients and 1516 controls in GWAS stage and 1994 GD patients and 2085 controls and 5033 GD patients and 5389...

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Asian People
Case-Control Studies
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 30176063
DOI: 10.1111/cen.13847

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