Article
East Asian variant of aldehyde dehydrogenase 2 is related to worse cardioprotective results after coronary artery bypass grafting.
Interactive cardiovascular and thoracic surgery - 1 Jan 2019
Gong Dingxu, Zhang Lin, Zhang Ying, Wang Fang, Zhou Xianliang, Sun Hansong
Abstract excerpt
OBJECTIVES: Aldehyde dehydrogenase 2 activity is associated with cardioprotection. Individuals carrying an East Asian variant of the ALDH2 genotype (ALDH2*2) have significantly reduced aldehyde dehydrogenase 2 activity. No previous studies have determined the effect of the ALDH2*2 genotype on cardioprotective results after coronary artery bypass grafting (CABG). METHODS: In total, 207 patients who underwent...
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