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Article

Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease.

Current drug targets - 1 Jan 2017

Liu Xiangwei, Sun Aijun

Abstract excerpt

BACKGROUND: Coronary heart disease is the leading cause of mortality and morbidity, incurring a major burden of medical care. Even with increasing application of emergent recanalization (PCI and CABG) therapy, ischemia and ischemic reperfusion injury remain as the dominant pathological process that damages cardiomyocytes. Mitochondrial Aldehyde dehydrogenase-2 (ALDH2) is a multifunctional enzyme catalyzing the...

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Identifiers

PMID: 27633387
DOI: 10.2174/1389450117666160912174417

Genes

ALDH2

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