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Article

Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease.

European heart journal - 1 Jul 2012

Zhang Hao, Gong Ding-xu, Zhang Yu-jian, Li Shou-jun, Hu Shengshou

Abstract excerpt

AIMS: About 40% of East Asians carry an aldehyde dehydrogenase-2*2 (ALDH2*2) allele, and the influence of the ALDH2*2 allele on human cardioprotection has not been studied. This study was designed to evaluate the effect of ALDH2*2 allele on cardioprotection of patients with congenital heart diseases after open-heart surgery. METHODS AND RESULTS: The right atrial appendage was harvested before performing...

Topics

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Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Cardiotonic Agents
Heart Defects, Congenital
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitochondria, Heart

Myocardial Reperfusion Injury

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Identifiers

PMID: 22507973
DOI: 10.1093/eurheartj/ehs061

Genes

ALDH2
ATF4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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