Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation.

Cell cycle (Georgetown, Tex.) - 1 Jan 2018

Roesley Siti Nur Ain, La Marca John E, Deans Andrew J, Mckenzie Lisa, Suryadinata Randy, Burke Peter, Portela Marta, Wang Hongyan, Bernard Ora, Sarcevic Boris, Richardson Helena E

Abstract excerpt

The SWI/SNF ATP-dependent chromatin-remodeling complex is an important evolutionarily conserved regulator of cell cycle progression. It associates with the Retinoblastoma (pRb)/HDAC/E2F/DP transcription complex to modulate cell cycle-dependent gene expression. The key catalytic component of the SWI/SNF complex in mammals is the ATPase subunit, Brahma (BRM) or BRG1. BRG1 was previously shown to be phosphorylated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinases

Share to Epistasis, Genetic

Share to Epithelium

Share to S Phase

Share to Trans-Activators

Share to Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 29963966
DOI: 10.1080/15384101.2018.1493414
PMCID: PMC6133315

Genes

CDK2
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation.PMID 29963966Read ↗

Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.Semantic proximity Read ↗

RNA-Seq Profiling Reveals Transcriptional Changes in Phosphorylation-Site Mutants of Brg1.Semantic proximity Read ↗

Essential Role of ARID2 Protein-containing SWI/SNF Complex in Tissue-specific Gene ExpressionSemantic proximity Read ↗

Transcriptional activation by pRB and its coordination with SWI/SNF recruitment.Semantic proximity Read ↗

SNR1 (INI1/SNF5) mediates important cell growth functions of the Drosophila Brahma (SWI/SNF) chromatin remodeling complex.Semantic proximity Read ↗

Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth ArrestSemantic proximity Read ↗

Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation.Semantic proximity Read ↗

Rb, whi it's not just for metazoans anymore.Semantic proximity Read ↗

Bromodomain-Containing Protein BRD4 Is Hyperphosphorylated in MitosisSemantic proximity Read ↗

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1.Semantic proximity Read ↗

The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.Semantic proximity Read ↗

The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.