Article
[A rare variant in the sortilin-related receptor 1 gene is associated with declined cognitive functions in the elderly].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2000
Stepanov V A, Bocharova A V, Vagaitseva K V, Marusin A V, Markova V V, Minaicheva L I, Zhukova I A, Zhukova N G, Alifirova V M, Makeeva O A
Abstract excerpt
AIM: To estimate the association of rs11218343 in the sortilin-related receptor 1 (SORL1) gene with cognitive performance in the elderly and with Alzheimer's disease (AD) in the Russian population. MATERIAL AND METHODS: A sample included 586 elderly people (mean age 70.9±5.7 years) without AD diagnosis and 100 patients with late-onset AD (mean age 72.1±7.8 years) from the Tomsk population. SORL1 rs11218343 was...
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