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Article

ORMDL3 and its implication in inflammatory disorders.

International journal of rheumatic diseases - 1 Jun 2018

Ma Xiaochun, Long Feng, Yun Yan, Dang Jie, Wei Shijun, Zhang Qian, Li Jinzhang, Zhang Haizhou, Zhang Wenlong, Wang Zhengjun, Liu Qiji, Zou Chengwei

Abstract excerpt

A growing body of evidence has suggested the genetic association of ORMDL3 gene (ORMDL Sphingolipid Biosynthesis Regulator 3) polymorphisms with a diverse set of inflammatory disorders that include bronchial asthma, inflammatory bowel disease, ankylosing spondylitis and atherosclerosis. Gene functional investigations have revealed the particular relevance of ORMDL3 in endoplasmic reticulum stress, lipid...

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Source

Identifiers

PMID: 29879314
DOI: 10.1111/1756-185X.13324

Genes

ORMDL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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ORMDL3 and its implication in inflammatory disorders.PMID 29879314Read ↗

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At last - linking ORMDL3 polymorphisms, decreased sphingolipid synthesis, and asthma susceptibility.Semantic proximity Read ↗

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