Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Mar 2023

Nowakowska Joanna, Olechnowicz Anna, Langwiński Wojciech, Koteluk Oliwia, Lemańska Żaneta, Jóźwiak Kacper, Kamiński Kacper, Łosiewski Wojciech, Stegmayr John, Wagner Darcy, Alsafadi Hani N, Lindstedt Sandra, Dziuba Maria, Bielicka Antonina, Graczyk Zuzanna, Szczepankiewicz Aleksandra

Abstract excerpt

BACKGROUND: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is the ORMDL3 gene confirmed in several GWA studies in several pediatric populations. OBJECTIVES: The purpose of this study was to analyze ORMDL3 variants and expression in childhood asthma in the Polish population. METHODS: In the study we included 416 subject, 223 asthmatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytokines

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Inflammation

Share to Membrane Proteins

Source

Identifiers

PMID: 35321632
DOI: 10.1080/02770903.2022.2056896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study.PMID 35321632Read ↗

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.Semantic proximity Read ↗

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.Semantic proximity Read ↗

Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma.Semantic proximity Read ↗

Single nucleotide polymorphisms in the ORM1-like 3 gene associated with childhood asthma in a Chinese population.Semantic proximity Read ↗

Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma.Semantic proximity Read ↗

GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness.Semantic proximity Read ↗

Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus.Semantic proximity Read ↗

Genetic variation in ORMDL3 gene may contribute to the risk of asthma: a meta-analysis.Semantic proximity Read ↗

Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population.Semantic proximity Read ↗

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.Semantic proximity Read ↗

17q21 locus and ORMDL3: an increased risk for childhood asthma.Semantic proximity Read ↗

Genes in asthma: new genes and new ways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.