Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Individuals with filaggrin-related eczema and asthma have increased long-term medication and hospital admission costs.

The British journal of dermatology - 1 Sept 2018

Soares P, Fidler K, Felton J, Tavendale R, Hövels A, Bremner S A, Palmer C N A, Mukhopadhyay S

Abstract excerpt

BACKGROUND: Eczema and asthma are chronic diseases with onset usually before the age of 5 years. More than 50% of individuals with eczema will develop asthma and/or other allergic diseases. Several loss-of-function mutations in filaggrin (FLG) have been identified in patients with eczema. However, the association of FLG with healthcare use is unknown. OBJECTIVES: To determine whether FLG mutations are associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Asthmatic Agents
Share to Eczema

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Filaggrin Proteins

Share to Health Care Costs

Share to Hospitalization

Share to Loss of Function Mutation

Share to S100 Proteins

Share to Scotland

Source

Identifiers

PMID: 29851030
DOI: 10.1111/bjd.16720

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Individuals with filaggrin-related eczema and asthma have increased long-term medication and hospital admission costs.PMID 29851030Read ↗

Filaggrin null mutations are associated with increased asthma severity in children and young adults.Semantic proximity Read ↗

The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study.Semantic proximity Read ↗

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.Semantic proximity Read ↗

Eczema severity in preadolescent children and its relation to sex, filaggrin mutations, asthma, rhinitis, aggravating factors and topical treatment: a report from the BAMSE birth cohort.Semantic proximity Read ↗

Analysis of rare coding variants in 470,000 UK Biobank participants reveals genetic associations with childhood asthma predispositionSemantic proximity Read ↗

Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults.Semantic proximity Read ↗

Filaggrin gene variants and atopic diseases in early childhood assessed longitudinally from birth.Semantic proximity Read ↗

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma.Semantic proximity Read ↗

Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk.Semantic proximity Read ↗

Filaggrin loss-of-function mutations are associated with early-onset eczema, eczema severity and transepidermal water loss at 3 months of age.Semantic proximity Read ↗

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure.Semantic proximity Read ↗

Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.