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Article

Strategies for fine-mapping complex traits.

Human molecular genetics - 15 Oct 2015

Spain Sarah L, Barrett Jeffrey C

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of robust and replicable genetic associations for complex disease. However, the identification of the causal variants that underlie these associations has been more difficult. This problem of fine-mapping association signals predates GWAS, but the last few years have seen a surge of studies aimed at pinpointing causal variants using both statistical...

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PMID: 26157023
DOI: 10.1093/hmg/ddv260
PMCID: PMC4572002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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