Article
Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity.
The pharmacogenomics journal - 1 Apr 2019
Li Ruowang, Kim Dokyoon, Wheeler Heather E, Dudek Scott M, Dolan M Eileen, Ritchie Marylyn D
Abstract excerpt
Identifying genetic variants associated with chemotherapeutic induced toxicity is an important step towards personalized treatment of cancer patients. However, annotating and interpreting the associated genetic variants remains challenging because each associated variant is a surrogate for many other variants in the same region. The issue is further complicated when investigating patterns of associated variants...
Topics
Join the communities discussing this publication.