Article
Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations.
Oncotarget - 23 Feb 2016
Sun Yi, Zhang Wei, Chen Yunqin, Ma Qin, Wei Jia, Liu Qi
Abstract excerpt
BACKGROUND: Clinical responses to anti-cancer therapies often only benefit a defined subset of patients. Predicting the best treatment strategy hinges on our ability to effectively translate genomic data into actionable information on drug responses. RESULTS: To achieve this goal, we compiled a comprehensive collection of baseline cancer genome data and drug response information derived from a large panel of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
