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Article

Systematic analysis of genotype-specific drug responses in cancer.

International journal of cancer - 15 Nov 2012

Kim Nayoung, He Ningning, Kim Changsik, Zhang Fan, Lu Yiling, Yu Qinghua, Stemke-Hale Katherine, Greshock Joel, Wooster Richard, Yoon Sukjoon, Mills Gordon B

Abstract excerpt

A systematic understanding of genotype-specific sensitivity or resistance to anticancer agents is required to provide improved patient therapy. The availability of an expansive panel of annotated cancer cell lines enables comparative surveys of associations between genotypes and compounds of various target classes. Thus, one can better predict the optimal treatment for a specific tumor. Here, we present a...

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Identifiers

PMID: 22422301
DOI: 10.1002/ijc.27529
PMCID: PMC4012336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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