Article
Identifying genetic variants that contribute to chemotherapy-induced cytotoxicity.
Pharmacogenomics - 1 Sept 2007
Hartford Christine M, Dolan M Eileen
Abstract excerpt
Patients treated with anticancer chemotherapy exhibit variation, both in terms of tumor response and the incidence and severity of adverse effects. The etiology of this variation is multifactorial with genetic factors likely contributing to a significant extent. Pharmacogenetic and genomic studies can be used to identify the genetic variants that contribute to interindividual variation in susceptibility to...
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