A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

doi:10.1097/MEG.0000000000001168

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

European journal of gastroenterology & hepatology - 1 Aug 2018

Hrdlickova Barbara, Mulder Chris J, Malamut Georgia, Meresse Bertrand, Platteel Mathieu, Kamatani Yoichiro, Ricaño-Ponce Isis, van Wanrooij Roy L J, Zorro Maria M, Jan Bonder Marc, Gutierrez-Achury Javier, Cellier Christophe, Zhernakova Alexandra, Nijeboer Petula, Galan Pilar, Withoff Sebo, Lathrop Mark, Bouma Gerd, Xavier Ramnik J, Jabri Bana, Bensussan Nadine C, Wijmenga Cisca, Kumar Vinod

Abstract excerpt

BACKGROUND: Approximately 5% of patients with celiac disease (CeD) do not respond to a gluten-free diet and progress to refractory celiac disease (RCD), a severe progression that is characterized by infiltration of intraepithelial T lymphocytes. Patients with RCD type II (RCDII) show clonal expansions of intraepithelial T lymphocytes that result in a poor prognosis and a high mortality rate through development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 7

Share to Diet, Gluten-Free

Share to Gastrointestinal Microbiome

Share to Intestine, Small

Share to Netherlands

Share to Paneth Cells

Share to Treatment Failure

Source

Open in PubMed Open full text

Identifiers

PMID: 29787419
DOI: 10.1097/MEG.0000000000001168
PMCID: PMC6373482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.PMID 29787419Read ↗

Oncogenetic Landscape Of Lymphomagenesis In Coeliac DiseaseSemantic proximity Read ↗

Expanded T cell clones with lymphoma driver somatic mutations in refractory celiac diseaseSemantic proximity Read ↗

Understanding Celiac Disease by Genomics.Semantic proximity Read ↗

Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac diseaseSemantic proximity Read ↗

CLONAL LYMPHOCYTE EXPANSIONS AND JAK-STAT PATHWAY MUTATIONS DEFINE A PATHOGENIC CONTINUUM DRIVING RESISTANCE TO GLUTEN-FREE DIET IN CELIAC DISEASESemantic proximity Read ↗

Celiac disease susceptibility: The genome and beyond.Semantic proximity Read ↗

Cellular and molecular bases of refractory celiac disease.Semantic proximity Read ↗

Immunophenotypic Spectrum and Genomic Landscape of Refractory Celiac Disease Type II.Semantic proximity Read ↗

Oncogenetic landscape of lymphomagenesis in coeliac diseaseSemantic proximity Read ↗

Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II.Semantic proximity Read ↗

Polygenic risk of refractory celiac disease type II and its association with autoimmune diseases: a phenome-wide association study in the UK Biobank.Semantic proximity Read ↗

Single cell transcriptome sequencing indicates the cellular heterogeneity of small intestine tissue in celiac diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.