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Article

Oncogenetic landscape of lymphomagenesis in coeliac disease

12 Feb 2021

Abstract excerpt

OBJECTIVE: Enteropathy-associated T-cell lymphoma (EATL) is a rare but severe complication of coeliac disease (CeD), often preceded by low-grade clonal intraepithelial lymphoproliferation, referred to as type II refractory CeD (RCDII). Knowledge on underlying oncogenic mechanisms remains scarce. Here, we analysed and compared the mutational landscape of RCDII and EATL in order to identify genetic drivers of...

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PMID: 33579790
DOI: 10.1136/gutjnl-2020-322935

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