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Article

Immunophenotypic Spectrum and Genomic Landscape of Refractory Celiac Disease Type II.

The American journal of surgical pathology - 1 Jul 2021

Soderquist Craig R, Lewis Suzanne K, Gru Alejandro A, Vlad George, Williams Eli S, Hsiao Susan, Mansukhani Mahesh M, Park David C, Bacchi Carlos E, Alobeid Bachir, Green Peter H, Bhagat Govind

Abstract excerpt

Refractory celiac disease type II (RCD II), also referred to as "cryptic" enteropathy-associated T-cell lymphoma (EATL) or "intraepithelial T-cell lymphoma," is a rare clonal lymphoproliferative disorder that arises from innate intraepithelial lymphocytes. RCD II has a poor prognosis and frequently evolves to EATL. The pathogenesis of RCD II is not well understood and data regarding the immunophenotypic spectrum...

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PMID: 33544565
DOI: 10.1097/PAS.0000000000001658

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