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Article

Genetic risk score of common genetic variants for impaired fasting glucose and newly diagnosed type 2 diabetes influences oxidative stress.

Scientific reports - 18 May 2018

Kim Minjoo, Kim Minkyung, Huang Limin, Jee Sun Ha, Lee Jong Ho

Abstract excerpt

We tested the hypothesis that the cumulative effects of common genetic variants related to elevated fasting glucose are collectively associated with oxidative stress. Using 25 single nucleotide polymorphisms (SNPs), a weighted genetic risk score (wGRS) was constructed by summing nine risk alleles based on nominal significance and a consistent effect direction in 1,395 controls and 718 patients with impaired...

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Identifiers

PMID: 29777116
DOI: 10.1038/s41598-018-26106-z
PMCID: PMC5959868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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