Article

SLC30A8 rare variant modify contribution of common genetic and lifestyle factors toward type 2 diabetes

2024-08-28

Abstract excerpt

This study aimed to investigate the modifying effects of rare genetic variants on the risk of type 2 diabetes in the context of common genetic and lifestyle factors. We conducted a comprehensive analysis of genetic and lifestyle factors associated with type 2 diabetes in a cohort of 146,284 Korean individuals. Among them, 4,603 individuals developed type 2 diabetes during the follow-up period of up to 18 years. We...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bf6450c4-7363-5b7e-a3ed-e94ca93bf6d6
DOI: 10.1101/2024.08.28.24312708

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SLC30A8 rare variant modify contribution of common genetic and lifestyle factors toward type 2 diabetesDOI 10.1101/2024.08.28.24312708Read

SLC30A8 Rare Variant Modify Contribution of Common Genetic and Lifestyle Factors toward Type 2 Diabetes Mellitus.Semantic proximity Read

Association of Polygenic Variants with Type 2 Diabetes Risk and Their Interaction with Lifestyles in Asians.Semantic proximity Read

SLC30A8 polymorphism and type 2 diabetes risk: evidence from 27 study groups.Semantic proximity Read

Polygenic Risk Score, Lifestyles, and Type 2 Diabetes Risk: A Prospective Chinese Cohort StudySemantic proximity Read

Gene-environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels.Semantic proximity Read

Influence of Diabetes Family History on the Associations of Combined Genetic and Lifestyle Risks with Diabetes in the Tohoku Medical Megabank Community-Based Cohort Study.Semantic proximity Read

Associations of Combined Genetic and Lifestyle Risks With Incident Type 2 Diabetes in the UK Biobank.Semantic proximity Read

The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians.Semantic proximity Read

Genetic Risk, Healthy Lifestyle Adherence, and Risk of Developing Diabetes in the Japanese Population.Semantic proximity Read

Genetic susceptibility, family history of diabetes and healthy lifestyle factors in relation to diabetes: A gene-environment interaction analysis in Chinese adults.Semantic proximity Read

Higher Genetic Risk for Type 2 Diabetes Is Associated With a Faster Decline of β-Cell Function in an East Asian Population.Semantic proximity Read

Genetic risk, adherence to a healthy lifestyle, and type 2 diabetes risk among 550,000 Chinese adults: results from 2 independent Asian cohorts.Semantic proximity Read