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Article

Real-World Utility of GWAS-Based Diabetes Mellitus Panel Testing.

International journal of molecular sciences - 26 Dec 2025

Jeong In Hwa, Hong Kyung-Won, Choi Ja-Eun, Shine Bo-Kyung

Abstract excerpt

This study evaluated the clinical utility of a polygenic risk score (PRS)-based multigene panel test for predicting diabetes mellitus (DM) in a healthy population. A total of 302 individuals underwent genetic testing using the HelloGene™ DM panel, which includes four DM-related single nucleotide polymorphisms (CDKAL1, HHEX, KCNQ1, and TCF7L2). PRS values were calculated using an algorithm developed from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41516154
DOI: 10.3390/ijms27010275
PMCID: PMC12785355

Genes

CDKAL1
HHEX
TCF7L2
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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