Article
Genetic-risk assessment of GWAS-derived susceptibility loci for type 2 diabetes in a 10 year follow-up of a population-based cohort study.
Journal of human genetics - 1 Dec 2016
Go Min Jin, Lee Young, Park Suyeon, Kwak Soo Heon, Kim Bong-Jo, Lee Juyoung
Abstract excerpt
To date, genome-wide meta-analyses have identified genetic susceptibility to type 2 diabetes mellitus (T2D) predominantly in populations of European ancestry. However, comprehensive genetic-risk assessment based on previous GWAS loci has not been fully tested in non-European populations. To evaluate whether a genetic-risk score (GRS) could improve T2D-risk prediction in the Korean population, a GRS (GRS-55) was...
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