Article
Gene-environment interaction in type 2 diabetes in Korean cohorts: Interaction of a type 2 diabetes polygenic risk score with triglyceride and cholesterol on fasting glucose levels.
Genetic epidemiology - 1 Jul 2022
Lim Ji Eun, Kang Ji-One, Ha Tae-Woong, Jung Hae-Un, Kim Dong Jun, Baek Eun Ju, Kim Han Kyul, Chung Ju Yeon, Rhee Sang Youl, Kim Mi Kyung, Kim Yeon-Jung, Park Taesung, Oh Bermseok
Abstract excerpt
Type 2 diabetes (T2D) is caused by genetic and environmental factors as well as gene-environment interactions. However, these interactions have not been systematically investigated. We analyzed these interactions for T2D and fasting glucose levels in three Korean cohorts, HEXA, KARE, and CAVAS, using the baseline data with a multiple regression model. Two polygenic risk scores for T2D (PRST2D ) and fasting...
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