Article
SLC30A8 Rare Variant Modify Contribution of Common Genetic and Lifestyle Factors toward Type 2 Diabetes Mellitus.
Diabetes & metabolism journal - 1 Mar 2026
Jang Hye-Mi, Hwang Mi Yeong, Park Yi Seul, Kim Bong-Jo, Kim Young Jin
Abstract excerpt
BACKGRUOUND: This study aimed to investigate the modifying effects of rare genetic variants on the risk of type 2 diabetes mellitus (T2DM) in the context of common genetic and lifestyle factors. METHODS: We conducted a comprehensive analysis of genetic and lifestyle factors associated with T2DM in a cohort of 146,284 Korean individuals. Among them, 4,603 individuals developed T2DM during the follow-up period of...
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