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Article

The hemodynamic response to constant dobutamine infusion: the effect of ADRB1 389 polymorphism and sex.

Pharmacogenetics and genomics - 1 Jun 2018

Yogev Dotan, Basheer Maamoun, Perlman Amichai, Blotnick Simcha, Caraco Yoseph, Muszkat Mordechai

Abstract excerpt

OBJECTIVES: Prolonged activation of the β-1 adrenergic receptor (ADRB1) is associated with receptor desensitization. This process has been suggested to have important pathophysiological and clinical implications in conditions such as congestive heart failure. The contribution of genetic factors to this process is a subject of ongoing research. We have previously shown that the ADRB1 389 polymorphism affects the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, beta-1

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Source

Identifiers

PMID: 29768300
DOI: 10.1097/FPC.0000000000000338

Genes

ADRB1
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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