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Article

Effects of polymorphisms in beta1-adrenoceptor and alpha-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Feb 2006

Nieminen Tuomo, Lehtimäki Terho, Laiho Jarno, Rontu Riikka, Niemelä Kari, Kööbi Tiit, Lehtinen Rami, Viik Jari, Turjanmaa Väinö, Kähönen Mika

Abstract excerpt

We tested whether the Arg389Gly and Ser49Gly polymorphisms of the beta1-adrenergic receptor gene ADRB1 and the T393C polymorphism of the G protein alpha-subunit gene GNAS1 modulate heart rate (HR) and blood pressure responses during an exercise stress test. The study population comprised 890 part...

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Identifiers

PMID: 16210433
DOI: 10.1152/japplphysiol.00899.2005

Genes

ADRB1
DAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16210433-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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