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Article

Functional effects of β₁-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration.

Clinical research in cardiology : official journal of the German Cardiac Society - 1 Feb 2011

Kindermann Michael, Seeland Ute, Ruhnke Patrick, Böhm Michael, Maack Christoph

Abstract excerpt

BACKGROUND: The relevance of the Arg389Gly- and Ser49Gly-β₁-adrenoceptor (AR) polymorphisms for cardiovascular function and pharmacotherapy is controversial. METHODS: Out of 38 healthy male volunteers who were screened for both types of the β₁-AR polymorphism 23 subjects underwent dobutamine stress echocardiography at baseline, after administration of metoprolol succinate (n = 18, 190 mg/day) and 44 h after...

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Source

Identifiers

PMID: 20821015
DOI: 10.1007/s00392-010-0221-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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