Article
Effects of sex and the common ADRB1 389 genetic polymorphism on the hemodynamic response to dobutamine.
Pharmacogenetics and genomics - 1 Nov 2015
Yogev Dotan, Basheer Maamoun, Blotnick Simcha, Caraco Yoseph, Muszkat Mordechai
Abstract excerpt
INTRODUCTION: The ADRB1 389 polymorphism affects responses to the β-1 adrenergic receptor (β1AR) agonist in vitro. Previous studies on its effect on the response to dobutamine stress echocardiography were conflicting. In addition, sex differences in the response to dobutamine have been suggested. The aim of this study was to determine whether the ADRB1 389 polymorphism affects the hemodynamic response to...
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