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Article

Gly389Arg polymorphism of beta1-adrenergic receptor is associated with the cardiovascular response to metoprolol.

Clinical pharmacology and therapeutics - 1 Oct 2003

Liu Jie, Liu Zhao-Qian, Tan Zhi-Rong, Chen Xiao-Ping, Wang Lian-Sheng, Zhou Gan, Zhou Hong-Hao

Abstract excerpt

OBJECTIVES: Our objectives were to determine whether the Gly389 polymorphism of the beta(1)-adrenergic receptor exhibits reduced responsiveness in vivo and to test the hypothesis that the Gly389Arg polymorphism affects the blood pressure and heart rate response to metoprolol. METHODS: beta(1)-Adrenergic receptor genotype was determined by polymerase chain reaction-restriction fragment length polymorphism assay....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14534524
DOI: 10.1016/S0009-9236(03)00224-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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