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Article

Genetic characterization of the HIV-1 reservoir after Vacc-4x and romidepsin therapy in HIV-1-infected individuals.

AIDS (London, England) - 24 Aug 2018

Winckelmann Anni, Morcilla Vincent, Shao Wei, Schleimann Mariane H, Hojen Jesper F, Schlub Timothy E, Denton Paul W, Østergaard Lars, Søgaard Ole S, Tolstrup Martin, Palmer Sarah

Abstract excerpt

OBJECTIVE: Therapeutic HIV-1 immunization followed by latency reversal has been suggested as a strategy to eradicate HIV-1. Here we investigate the phylogenetic composition of the HIV-1 regions targeted by the therapeutic HIV-1 peptide vaccine Vacc-4x in participants in a clinical trial. DESIGN: Seventeen participants on suppressive antiretroviral therapy were vaccinated with six doses of Vacc-4x followed by...

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Identifiers

PMID: 29762162
DOI: 10.1097/QAD.0000000000001861
PMCID: PMC6072375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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