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Article

Romidepsin-induced HIV-1 viremia during effective antiretroviral therapy contains identical viral sequences with few deleterious mutations.

AIDS (London, England) - 27 Mar 2017

Winckelmann Anni, Barton Kirston, Hiener Bonnie, Schlub Timothy E, Shao Wei, Rasmussen Thomas A, Østergaard Lars, Søgaard Ole S, Tolstrup Martin, Palmer Sarah

Abstract excerpt

OBJECTIVE: To investigate the origin of the HIV-1 viremia induced by the latency-reversing agent romidepsin. DESIGN: Six individuals on suppressive antiretroviral therapy received romidepsin administered intravenously once weekly for 3 consecutive weeks. CD4 T cells were obtained at baseline, following the second and third romidepsin infusion, and 10 weeks after the final romidepsin treatment. Plasma samples were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibiotics, Antineoplastic

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Share to env Gene Products, Human Immunodeficiency Virus

Share to HIV Core Protein p24

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Source

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Identifiers

PMID: 28272134
DOI: 10.1097/QAD.0000000000001400
PMCID: PMC5345886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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