Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Immunodeficiency Virus Type 1 Population Genetics and Adaptation in Newly Infected Individuals

31 Dec 2008

Abstract excerpt

Studies on human immunodeficiency virus type 1 (HIV-1) diversity are critical for understanding viral pathogenesis and the emergence of immune escape variants and for design of vaccine strategies. To investigate HIV-1 population genetics, we used single-genome sequencing to obtain pro-pol and env sequences from longitudinal samples (n = 93) from 14 acutely or recently infected patients. The first available sample...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19116249
DOI: 10.1128/jvi.01960-08

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Immunodeficiency Virus Type 1 Population Genetics and Adaptation in Newly Infected IndividualsPMID 19116249Read ↗

Rapid Reversion of Sequence Polymorphisms Dominates Early Human Immunodeficiency Virus Type 1 EvolutionSemantic proximity Read ↗

Population genomics of intrapatient HIV-1 evolution.Semantic proximity Read ↗

HLA-Associated Clinical Progression Correlates with Epitope Reversion Rates in Early Human Immunodeficiency Virus InfectionSemantic proximity Read ↗

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.Semantic proximity Read ↗

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy.Semantic proximity Read ↗

Viral evolution and escape during acute HIV-1 infection.Semantic proximity Read ↗

Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs.Semantic proximity Read ↗

Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.Semantic proximity Read ↗

Evolutionary and immunological implications of contemporary HIV-1 variation.Semantic proximity Read ↗

Genetic and antigenic features of the transmitted virus.Semantic proximity Read ↗

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infectionSemantic proximity Read ↗

Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.