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Article

Sieve analysis in HIV-1 vaccine efficacy trials.

Current opinion in HIV and AIDS - 1 Sept 2013

Edlefsen Paul T, Gilbert Peter B, Rolland Morgane

Abstract excerpt

PURPOSE OF REVIEW: The genetic characterization of HIV-1 breakthrough infections in vaccine and placebo recipients offers new ways to assess vaccine efficacy trials. Statistical and sequence analysis methods provide opportunities to mine the mechanisms behind the effect of an HIV vaccine. RECENT FINDINGS: The release of results from two HIV-1 vaccine efficacy trials, Step/HVTN-502 (HIV Vaccine Trials Network-502)...

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Identifiers

PMID: 23719202
DOI: 10.1097/COH.0b013e328362db2b
PMCID: PMC3863593

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