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Article

Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals

29 Nov 2018

Abstract excerpt

OBJECTIVES: Reversing HIV-1 latency has been suggested as a strategy to eradicate HIV-1. We investigated the effect of romidepsin on the HIV transcription profile in participants from the REDUC part B clinical trial. DESIGN: Seventeen participants on suppressive antiretroviral therapy were vaccinated with six doses of the therapeutic vaccine Vacc-4x followed by treatment with three doses of romidepsin. Samples...

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PMID: 30531314
DOI: 10.1097/qad.0000000000002083

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