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Article

High-Content Imaging Phenotypic Screen for Neurogenesis Using Primary Neural Progenitor Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Wu Li Sharon, Li Jingjun

Abstract excerpt

Neurogenesis phenotypic screen of small-molecule library enables the discovery of small-molecule inducers, and identification of associated biological targets and pathways that control neuronal formation from neural progenitor cells (NPCs). Here, we describe protocols for preparing mouse embryonic NPCs, setting up a high-content imaging assay that quantifies the production of Tuj1-labeled neurons, and analysis of...

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Identifiers

PMID: 29736713
DOI: 10.1007/978-1-4939-7847-2_8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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