Article
Image-based high-content screening in drug discovery.
Drug discovery today - 1 Aug 2020
Lin Sean, Schorpp Kenji, Rothenaigner Ina, Hadian Kamyar
Abstract excerpt
While target-based drug discovery strategies rely on the precise knowledge of the identity and function of the drug targets, phenotypic drug discovery (PDD) approaches allow the identification of novel drugs based on knowledge of a distinct phenotype. Image-based high-content screening (HCS) is a potent PDD strategy that characterizes small-molecule effects through the quantification of features that depict...
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