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Article

Chromosomal barcoding as a tool for multiplexed phenotypic characterization of laboratory evolved lineages.

Scientific reports - 3 May 2018

Jahn Leonie Johanna, Porse Andreas, Munck Christian, Simon Daniel, Volkova Svetlana, Sommer Morten Otto Alexander

Abstract excerpt

Adaptive laboratory evolution is an important tool to evolve organisms to increased tolerance towards different physical and chemical stress. It is applied to study the evolution of antibiotic resistance as well as genetic mechanisms underlying improvements in production strains. Adaptive evolution experiments can be automated in a high-throughput fashion. However, the characterization of the resulting lineages...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29725068
DOI: 10.1038/s41598-018-25201-5
PMCID: PMC5934437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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