Article
Genetic Analysis of TREM2 Variants in Tunisian Patients with Alzheimer's Disease.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2018
Landoulsi Zied, Ben Djebara Mouna, Kacem Imen, Sidhom Youssef, Kefi Rym, Abdelhak Sonia, Gargouri-Berrechid Amina, Gouider Riadh
Abstract excerpt
OBJECTIVE: Rare variants in the TREM2 gene have been reported to significantly increase the risk of Alzheimer's disease in Caucasian populations. Hitherto, this association was not studied in North African populations. In this work, we aimed to study the association between TREM2 exon 2 variants and the risk of late-onset Alzheimer's disease (LOAD) in a Tunisian population. SUBJECTS AND METHODS: We sequenced exon...
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