A Missense Variant in TREML2 Reduces Risk of Alzheimer's Disease in a Han Chinese Population.

doi:10.1007/s12035-016-9706-8

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A Missense Variant in TREML2 Reduces Risk of Alzheimer's Disease in a Han Chinese Population.

Molecular neurobiology - 1 Mar 2017

Jiang Teng, Wan Yu, Zhou Jun-Shan, Tan Meng-Shan, Huang Qing, Zhu Xi-Chen, Lu Huan, Wang Hui-Fu, Chen Qi, Tan Lin, Zhang Ying-Dong, Tan Lan, Yu Jin-Tai

Abstract excerpt

Recently, Benitez and colleagues re-analyzed whole-exome sequencing data and revealed that a coding missense variant (rs3747742-C) in triggering receptor expressed on myeloid cells-like 2 (TREML2) gene reduced late-onset Alzheimer's disease (LOAD) risk in Caucasians. To date, no study was carried out to test this association in other ethnic groups and populations, including Han Chinese. Therefore, the aim of the...

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PMID: 26797517
DOI: 10.1007/s12035-016-9706-8

Genes

APOE
TREML2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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