Article
Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer's disease in Han Chinese individuals.
Neurobiology of aging - 1 Apr 2014
Yu Jin-Tai, Jiang Teng, Wang Ying-Li, Wang Hui-Fu, Zhang Wei, Hu Nan, Tan Lin, Sun Lei, Tan Meng-Shan, Zhu Xi-Chen, Tan Lan
Abstract excerpt
Recent studies have reported that a rare mutation of triggering receptor expressed on myeloid cells 2 gene (TREM2 [rs75932628-T]) has significantly increased the risk of late-onset Alzhemier's disease (LOAD) in European-descendent population. To date, no study has investigated the association between rare mutations of TREM2 and LOAD risk in non-European population. Here, we sequenced exon2 of TREM2 in the...
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