Article
TREM2 mutations are rare in a French cohort of patients with frontotemporal dementia.
Neurobiology of aging - 1 Oct 2013
Lattante Serena, Le Ber Isabelle, Camuzat Agnès, Dayan Sarah, Godard Chloé, Van Bortel Inge, De Septenville Anne, Ciura Sorana, Brice Alexis, Kabashi Edor
Abstract excerpt
Homozygous mutations in TREM2 have been recently identified by exome sequencing in families presenting with frontotemporal dementia (FTD)-like phenotype. No study has evaluated the exact frequency of TREM2 mutations in cohorts of FTD patients so far. We sequenced TREM2 in 175 patients with pure F...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.